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Health Benefits DMSO: Dimethyl Sulfoxide Dimethyl Sulfoxide Also known as: DMSO; Dimethylsulphoxide; RIMSO Description Dimethyl Sulfoxide is a Sulfuric Compound originally used as an industrial solvent that since the 1960's has been recognized for various therapeutic benefits - its usage has been highly controversial.
Detoxification DMSO (administered intravenously) facilitates the excretion of excessive accumulated Amyloid (amyloidosis).
Excretory System
DMSO (50% solution applied
topically to the Feet) alleviates Foot Odour (Bromidrosis) [observations
to date indicate that the longer that the DMSO solution is allowed to
remain in contact with the feet, the longer thereafter the Foot Odour
subsides]. DMSO treatment for IC should be administered by a suitably qualified medical practitioner - the usual treatment protocol involves the administration of a 50% solution of DMSO intravesically (i.e. instilled into the Urinary Tract) every 2 weeks for 2 sessions of 4 treatments each. Immune System DMSO helps to alleviate Allergies (by "unfolding" Cell Membranes, DMSO permits more Antigens to attach to Cell Membranes, where they are more effectively neutralized by Antibodies).
Metabolism DMSO deactivates Hydroxyl Free Radicals (DMSO combines with Hydroxyl Free Radicals to form Dimethyl Sulfone and Water which are then readily excreted from the body). Musculoskeletal System DMSO (either applied topically or consumed orally) minimizes the damage caused by crushing injuries such as Bruises and pulled or wrenched Muscles :
- DMSO is a powerful scavenger of
Hydroxyl Free Radicals which are responsible for much of the damage caused
in these injuries. DMSO alleviates Rheumatoid Arthritis (by deactivating Hydroxyl Free Radicals which are one of the principal causes of the Inflammation and Pain associated with Rheumatoid Arthritis). Nervous System DMSO (DMSO/Amino Acid Combination) therapy partially reverses some of the abnormalities that occur in Down's Syndrome [scientific research - humans: DMSO/Amino Acid therapy causes a tendency towards accelerated maturity in Down's Syndrome children treated, with marked progress in language integration. In some cases, this therapy causes the physical appearance of Down's Syndrome children to more closely resemble that of normal children]. DMSO markedly reduces the formation of the abnormal Antibodies that are characteristic of Myasthenia Gravis [scientific research - animals: note that this finding has not yet been confirmed for humans]: - As a secondary means of alleviating Myasthenia Gravis, DMSO also inhibits the actions of Cholinesterases (similarly to the Anticholinesterase Pharmaceutical Drugs employed by orthodox medicine in the treatment of Myasthenia Gravis). DMSO alleviates Pain by impeding the conduction of Nerve Impulses relating to the Pain sensation in the smaller Nerve Fibers.
DMSO (1 gram per kg of body weight administered intravenously into the Spinal Cord in a 40% solution within 1 hour of the occurrence of quadriplegia) helps to prevent Paralysis following injuries to the Spinal Cord that would otherwise cause Quadriplegia [scientific research - animals & humans: this treatment often results in total avoidance and reversal of paralysis/quadriplegia].
Respiratory System
DMSO (placed directly into the
nostrils) can open the blocked Sinuses that are associated with Sinusitis
[scientific observation - Skin DMSO (applied topically) alleviates the lesions that occur as a result of Herpes Zoster (Shingles).
DMSO (applied topically) potently alleviates Scleroderma (where Scleroderma affects the Skin). DMSO Enhances the Function of these Substances DMSO enhances the bioavailability of many substances (it has the capability to transport many therapeutic substances across the body's Cell Membranes without altering the integrity of Cell Membranes). By increasing their bioavailability, DMSO permits a lower dosage of some drugs than would otherwise be required. Enzymes DMSO inhibits the release of Cholinesterases (i.e. it possesses similar properties to Pharmaceutical Anticholinesterases). Hormones When exogenous forms of endogenous Steroids (including Testosterone and the Hydrocortisone form of Cortisone) are dissolved in DMSO prior to topical application, their topical bioavailability increases by 300% [scientific research - humans]. Immune System Chemicals DMSO can enter Cells to prime or activate the sub-cellular mechanisms involved in the production and release of Migration Inhibitory Factor (MIF) and in addition, produces a cofactor that enhances MIF or has MIF-like activity. Neurotransmitters DMSO facilitates the transport of (supplemental) Gamma Aminobutyric Acid (GABA) across the Blood-Brain Barrier (without DMSO as a carrier-vehicle, GABA poorly crosses the Blood-Brain Barrier). Pharmaceutical Drugs
DMSO enhances the bioavailability
and effectiveness of many Anti-Viral Pharmaceutical Drugs (DMSO
facilitates their transport directly across Cell Membranes into Cells
where they are most potent against Viruses). These Substances Enhance the Function of DMSO Antioxidants Antioxidants counteract DMSO's tendency to convert to Sulfoxide Free Radicals.
Side Effects of DMSO Therapy Excretory System DMSO (temporarily) causes Halitosis in the form of a garlic-like odor of the breath (this odor is very unpleasant and appears to be the major practical drawback in the usage of DMSO). Free Radicals After chemically reacting with Hydroxyl Free Radicals, DMSO is converted to a Sulfoxide Free Radical. Skin Itching is a common side effect of topical DMSO therapy - this side effect can usually be avoided by diluting the concentration of DMSO. Skin Rashes are a common side effect of topical DMSO therapy - this side effect can usually be avoided by diluting the concentration of DMSO. Myths Dispelled Eyes/Eyesight DMSO is often avoided by orthodox medical practitioners due to UNFOUNDED fears that it can cause Cataracts and other changes within the human Eye: - This aspect of DMSO toxicology has been extensively tested in both animals and humans: the results clearly show that DMSO does NOT cause Cataracts in humans even at extremely high dosages for periods up to two years. No adverse changes were found in human or monkey eyes after prolonged, high levels (up to 30 times the usual dosage) of DMSO treatment.
Bioavailability DMSO has the ability to pass through every tissue and Cell Membrane of the body except the Enamel of Teeth, fingernails and Hair without destroying the integrity of these tissues and Cell Membranes (i.e. it is a membrane penetrate). DMSO also permits the passage of a number of compounds across the barriers of Cell Membranes.
Orally ingested DMSO is also rapidly absorbed and reaches a blood serum peak in 4 hours and becomes undetectable after 120 hours.
DMSO is excreted from the body partly in an unchanged state and partly as its metabolite - Dimethyl Sulfoxone (DMSO2). DMSO as part of the Global Sulfur Cycle DMSO is an intermediate product of the methyl-S-methane global Sulfur cycle which distributes bioavailable Sulfur for all animal and plant life. Approximately 85% of Sulfur (for life) is derived from the pathway: - Sulfonium Salts > Dimethylsulfide > Dimethyl Sulfoxide (DMSO) > Methylsulfonylmethane (MSM) - Sulfonium Salts (produced by phytoplankton in Water) yield the volatile thioether named Dimethylsulfide which is released into the upper atmosphere. - Sunlight catalyzes the oxidation of Dimethylsufide to DMSO. - DMSO is further oxidized in the upper atmosphere (by Sunlight) to form MSM. - This MSM is then concentrated into raindrops which return to the surface of the earth. - Plants absorb and accumulate this MSM (and use some of this MSM for bulding Sulfuric compounds). Forms of DMSO DMSO is manufactured in liquid and gel forms. Dosage Recommendations Long Term Dosage Reduction Less DMSO is required to achieve therapeutic results as time passes (i.e. the cumulative effects of DMSO appear to increase with the passage of time). Topical Therapeutic Dosage Protocol The liquid form of DMSO is the most effective form of topical DMSO application, although most people prefer the gel form.
The Face and Neck are more sensitive to topical DMSO than other parts of the body - the maximum concentration of DMSO for application to the Face or Neck should be no greater than 50%.
The Skin must be clean, dry and
unbroken before topical application of DMSO.
The usual oral dosage of DMSO is 1
- 2 teaspoons (5 - 10 ml) per day. Intravenous Injections of DMSO Dosage Protocol Up to 20 cc DMSO that has been diluted to a 25% concentration with sterile water is often administered via intravenous injection by suitably trained physicians for the treatment of the more serious degenerative diseases.
Intravenous Drip DMSO Dosage Protocol The slow intravenous drip method is applied over a 2-3 hour period. It involves the addition of 50-100 cc DMSO to a 500 cc glucose or saline solution, dripped into a vein in the patient's arm. This method should only be administered by a suitably qualified physician. Commercial Availability of DMSO Industrial Grade DMSO Caution: many of the industrial grade DMSO solutions intended for use as solvents have an acid or Acetone contamination of several percent. Acetone contamination can lead to serious medical consequences - because of its small molecular weight, Acetone is readily carried into the blood by Acetone-contaminated DMSO. Source of Commercial DMSO In the USA, commercially manufactured DMSO is derived from Lignin. DMSO/Water Combinations
Brand Composition Description
Brand Country Available
Description
Ipran is the trade name of a vasoactive DMSO product, however this product has not been approved for use in the USA.
DMSO's Chemical Structure
Molecular weight: 78.15
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